A weight difference was observed among African American versus non-African Americans harboring common EGFR mutations 784 kg vs. The researchers decided to account for this raising their eGFR by 159 percent.
Egfr Understanding Your Lab Values Renadyl Blog
53 suggests stage 3 kidney damage - moderate reduction in GFR.
Egfr african american vs non african american. For any given individual a black individual who has the same serum creatinine as. An eGFR of less than 15 indicates kidney failure and requires prompt medical care. Its the same as having curly hair versus straight hair.
GFR African American vs non AA Anonymous The eGFR is calculated using isotope dilution mass spectrometry IDMS-traceable serum creatinine measurements and the patients age 18 years and older gender and race African American vs non-African American according to the Chronic Kidney Disease Epidemiology Collaboration CKD-EPI equation. This is based on different muscle masses between different races. While African Americans represent 35 of people receiving dialysis in the United States they are less likely to be identified as kidney transplant candidates compared to Non-Hispanic Whites.
What is the controversy over using race in measuring eGFR. Race is used to estimate. Many different equations can be used to derive an estimated glomerular filtration rate eGFR.
It is usually ordered along with several other test when the kidney status is evaluated. Its simply a genetic expression that branched off millenia ago. The estimating equation for the glomerular filtration rate eGFR uses a different correcting factor for black African American individuals and individuals who are of other races non-African American.
The eGFR indicates how well the kidneys are filtering waste from the blood and it is calculated using a formula that includes age ethnicity creatinine level gender height and weight. EGFR for African American non-African American GFR glomerular filtration rate is equal to the total of the filtration rates of the functioning nephrons in the kidney it is usually accepted as the best overall index of kidney function. SCr-1154x age-0203x 0742 if female x 1210 if African American Assume an American white and an African American have the same serum creatinine level are at the same age and weight if the American white gets a GFR value 65 mLmin173 the African American gets a GFR value 7865 mLmin173.
EGFR if African American 34 mLmin173 m 2 eGFR if non-African American 28 mLmin173 m 2 Sample eGFR report for a 63-year-old woman identified as African American Creatinine 182 mgdL. Choose the one that best applies to you. Leidner1 1Departments of Medicine and Biostatistics University Hospitals - Case Medical Center Case Western Reserve University Cleveland OH USA.
For this reason a creatinine number may be slightly higher in young males. If female x 1210 if African American The equation was re-expressed in 2005 for use with a standardized serum creatinine assay which yields 5 lower values for serum creati-nine concentration4 6 GFR 175 x Standardized S Cr-1154 x age-0203 x 0742 if female x 1210 if African American GFR is expressed in mLmin173 m2 S Cr is. EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data Bradley T.
Values for both African American and non-African American individuals are reported for each patient. Some labs will report two values African American and non-African American. Pennell2 Balazs Halmos3 Rom S.
P 0051 but the difference was insignificant in terms of the uses of EGFR TKIs P 40 among those with metastatic NSCLC with common EGFR mutations. They called their formula the CKD-EPI equation and published it in the Annals of Internal Medicine in 2009. Also normal GFR will vary among ethnic groups.
Values less than 60 mLmin173 m 2 are consistent with chronic kidney disease and values less than 15 mLmin173 m 2 are consistent with kidney failure. Male with Creatinine09mgdL. Clifford1 Pingfu Fu1 Nathan A.
All equations will provide a range of values between 0 and. An eGFR below 60 mlmin suggests that some kidney damage has occurred normal values are 90-120 mlmin. African Americans have on average higher muscle mass than white Americans.
When a person has either diabetes or hypertension or there is other reason to monitor the kidneys it is usually ordered. It is a genetic difference based on evolution. The eGFR Glomurular Filtration Rate is one of those rare lab tests that have different reference ranges for African Americans versus non African Americans.
A normal eGFR ranges from 90 to 120 milliliters per minute per 173 square meters notes MedlinePlus. GFR 186 x Stand. HelloThe eGFR test is used to screen for and detect early kidney damage and to monitor kidney status.
The eGFR non -African American is a test that is ordered to check for early kidney damage and to monitor kidney function. Working as a Doctor who Cares since 2001. Numbers will be higher than that of females.
African Americans also have their eGFR numbers adjusted as their creatinine can be higher and still within a normal range. Measured GFR is the best way to report kidney function but this is too complicated for routine medical care. EGFR Normal Range.
Generally males have greater muscle mass so their creatinine.